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HeLP Trial
Heat Loss Prevention (HeLP) in the delivery room: A randomized controlled trial of polyethylene occlusive skin wrapping in very preterm infants. Vohra S, Roberts RS, Zhang B, et al. J Pediatr (Dec 2004); 145: 750-3.
Objectives To determine if polyethylene occlusive skin wrapping of very
preterm infants prevents heat loss after delivery better than conventional
drying and to evaluate if any benefit is sustained after wrap removal.
Study design This was a randomized controlled trial of infants <28
weeks' gestation. The experimental group was wrapped from the neck down. Only
the head was dried. Control infants were dried completely. Rectal temperatures
were compared on admission to the neonatal intensive care unit immediately
after wrap removal and 1 hour later.
Results Of 55 infants randomly assigned (28 wrap, 27 control), 2 died
in the delivery room and 53 completed the study. Wrapped infants had a higher
mean rectal admission temperature, 36.5°C (SD, 0.8°C), compared with 35.6°C
(SD, 1.3°C) in control infants (P=.002). One hour later, mean rectal
temperatures were similar in both groups (36.6°C, SD, 0.7°C vs. 36.4°C, SD,
0.9°C, P=.4). Size at birth was an important determinant of heat loss:
Mean rectal admission temperature increased by 0.21°C (95% CI, 0.04 to 0.4)
with each 100-g increase in birth weight.
Conclusions Polyethylene occlusive skin wrapping prevents rather than
delays heat loss at delivery in very preterm infants.
Comment: It appears that placing small premature infants in
a plastic bag after delivery does a better job of keeping them warm than does
drying them. Be careful that the plastic bag you are using does not contain
any of the plasticizer materials (like DEHP) that are thought to cause
neurotoxicity and other untoward effects in patients. ABK
Date: 28 Feb 2005
Time: 17:49:18
Would you be able to give me further infromation on the use of the plastic bags
in the trial please. My questions are:
1) where would one get the plastic bags from
2) what would be your recommended guideline on using the plastic bag (ie.
practical issues)
3) would your recommended guideline be the same as the one used in the trial
I would be grateful for your advise as we are thinking of using plastic bags in
our unit in Southampton.
UserName: Dr Ezam MAT ALI
Institution: Neonatal Unit, Princess Anne Hospital, Southampton
telephone: 07900494922
email: DrEzamAli@aol.com
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