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Oral vs Parenteral Vitamin K
Controversies Concerning
Vitamin K and the Newborn. AAP Policy Statement. Committee on Fetus and
Newborn. Pediatrics (July 2003); 112:191-2.
Prevention of early vitamin K deficiency bleeding (VKDB) of the
newborn, with onset at birth to 2 weeks of age (formerly known as
classic hemorrhagic disease of the newborn), by oral or parenteral
administration of vitamin K is accepted practice. In contrast, late
VKDB, with onset from 2 to 12 weeks of age, is most effectively
prevented by parenteral administration of vitamin K. Earlier concern
regarding a possible causal association between parenteral vitamin K
and childhood cancer has not been substantiated. This revised
statement presents updated recommendations for the use of vitamin K
in the prevention of early and late VKDB.
Comment:
The
recommendation remains unchanged.
Oral
Vitamin K is still NOT recommended due to the higher risk of late-onset VKDB.
ABK.
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