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Preterm Rupture of Membranes
Editor’s Note:
The topic of Preterm Premature Rupture of Membranes (PPROM) was the subject of the Dec 2001 issue of Clinics in Perinatology. Since neonatologists are occasionally called upon to advise obstetricians or counsel families with this condition, I felt that an update on the latest recommendations might be helpful. ABKAntenatal Steroids with PPROM
Vidaeff AC, Ranim SM, and Gillstrap LC. Clinics in Perinatology (Dec 2001); 28:797-805.
Antenatal corticosteroids are currently recommended for women with PPROM at 24 – 32 weeks gestation in the absence of clinical chorioamnionitis. There is no data to suggest beneficial effects of antenatal steroids at < 23 weeks or > 34 weeks. Repeated courses of antenatal corticosteroids are not recommended due to concerns of possibly increasing infectious complications and of possible effects on growth and neurodevelopmental outcome. There is little doubt remaining about the safety and efficacy of antenatal corticosteroids in the setting of preterm rupture of membranes.
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