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Preterm Rupture of Membranes
Editor’s Note:
The topic of Preterm Premature Rupture of Membranes (PPROM) was the subject of the Dec 2001 issue of Clinics in Perinatology. Since neonatologists are occasionally called upon to advise obstetricians or counsel families with this condition, I felt that an update on the latest recommendations might be helpful. ABKTocolysis with PPROM
Fontenot T. and Lewis DF. Clinics in Perinatology (Dec 2001); 28:787-96.
Patients with PPROM who receive prophylactic tocolytic therapy are significantly more likely to be undelivered at 48 hours (82% vs. 62.5%, p=0.0002). This allows time for corticosteroid administration and possibly for maternal transport. Long term tocolysis in this setting is not likely to be effective, and the majority of patients with PPROM can be expected to deliver within a week. The short-term use of tocolytics did not increase the rate of maternal or neonatal infections in these patients.
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